Description

2',3',5'-Trifluoropropiophenon is a high-purity fluorinated aromatic ketone building block, identified by CAS NO 243666-17-3. This compound is valued for its unique trifluoromethyl-substituted aromatic structure, which imparts desirable electronic and steric properties for advanced synthesis. It is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, where the fluorine atoms can enhance biological activity and environmental stability.
• Material Science Precursor: Serves as a monomer or precursor for specialty polymers and liquid crystals that require fluorinated aromatic components.
• Organic Synthesis Reagent: Employed in cross-coupling reactions, carbonyl chemistry, and as a scaffold for constructing complex fluorinated molecules in academic and industrial R&D.
• Fluorine Chemistry Studies: Utilized as a model compound to study the effects of multiple fluorine substitutions on aromatic ring reactivity and physical properties.

Basic Information

Product Name	2',3',5'-Trifluoropropiophenon
CAS No.	243666-17-3
Molecular Formula	C9H7F3O
Molecular Weight	188.15 g/mol
Synonyms	1-(2,3,5-Trifluorophenyl)propan-1-one; 2,3,5-Trifluoropropiophenone; Propiophenone, 2',3',5'-trifluoro-; 2,3,5-Trifluoro-1-phenyl-1-propanone; α-Oxobutane, 2,3,5-trifluoro derivative; 2,3,5-Trifluorophenyl ethyl ketone; (2,3,5-Trifluorophenyl)propan-1-one
EINECS	Contact for details

Quality Control

Our 2',3',5'-Trifluoropropiophenon is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, GC for residual solvents, and NMR/IR for structural confirmation, to ensure it meets the stringent requirements of research and process development. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.