Description

2,3,4-Trifluorophenylacetic Acid is a versatile fluorinated aromatic building block of significant importance in advanced organic synthesis. Its value lies in the trifluoromethylphenyl moiety, which is a key pharmacophore for modulating the lipophilicity, metabolic stability, and bioavailability of target molecules. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system, anti-inflammatory agents, and other therapeutic areas where fluorine substitution is beneficial.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides, where the fluorine atoms enhance biological activity and environmental stability.
• Liquid Crystal Materials: Serves as a building block for fluorinated liquid crystals used in display technologies, owing to the influence of fluorine on molecular polarity and alignment.
• Organic Electronics: Employed in the research and production of materials for organic light-emitting diodes (OLEDs) and semiconductors, where fluorinated aromatics improve electron transport properties.
• Advanced Material Research: Acts as a specialty monomer or modifier in polymers and coatings to impart specific chemical resistance, surface energy, or optical properties.
• Chemical Research & Development: A valuable reagent for medicinal chemistry and process chemistry, enabling structure-activity relationship (SAR) studies and route scouting for complex molecules.

Basic Information

Product Name	2,3,4-Trifluorophenylacetic Acid
CAS No.	243666-12-8
Molecular Formula	C8H5F3O2
Molecular Weight	198.12 g/mol
Synonyms	(2,3,4-Trifluorophenyl)acetic Acid; 2-(2,3,4-Trifluorophenyl)acetic Acid; α-(2,3,4-Trifluorophenyl)acetic Acid; 2,3,4-Trifluorobenzeneacetic Acid; 243666-12-8; 2,3,4-Trifluoro-Phenylacetic Acid
EINECS	Contact for details

Quality Control

Our 2,3,4-Trifluorophenylacetic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases, oxidizing agents, and heat sources. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.