Description

4-(Difluoromethoxy)Phenylacetic Acid is a high-purity fluorinated aromatic building block of significant interest in advanced organic synthesis. Its core value lies in the unique reactivity and physicochemical properties imparted by the difluoromethoxy group, which is a key motif in modern medicinal and agrochemical design. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in areas targeting metabolic and inflammatory diseases.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides and fungicides, where the difluoromethoxy group can enhance bioavailability and stability.
• Liquid Crystal Materials: Serves as a precursor in the production of fluorinated liquid crystals for advanced display technologies.
• Organic Electronics: Employed in the synthesis of specialized monomers and polymers for electronic applications due to its electronic properties.
• Chemical Research & Development: A versatile reagent for exploring new fluorination methodologies and constructing complex molecular architectures in academic and industrial labs.
• Fine Chemical Production: Used in the custom synthesis of specialty chemicals and complex organic molecules for various high-value industrial applications.

Basic Information

Product Name	4-(Difluoromethoxy)Phenylacetic Acid
CAS No.	243659-15-6
Molecular Formula	C9H8F2O3
Molecular Weight	202.16 g/mol
Synonyms	2-[4-(Difluoromethoxy)phenyl]acetic Acid; 4-(Difluoromethoxy)benzeneacetic Acid; α-(4-(Difluoromethoxy)phenyl)acetic Acid; (4-(Difluoromethoxy)phenyl)acetic Acid; DFMPAA; p-(Difluoromethoxy)phenylacetic Acid; 243659-15-6; Benzeneacetic acid, 4-(difluoromethoxy)-
EINECS	Contact for details

Quality Control

Our 4-(Difluoromethoxy)Phenylacetic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high chemical purity and consistent performance. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.