Description

Ethyl 2,2-Difluoro-2-(4-Nitrophenyl)Acetate is a specialized fluorinated organic building block of significant interest in advanced synthetic chemistry. Its molecular architecture, featuring both difluoroacetate and nitrophenyl moieties, makes it a versatile precursor for constructing complex molecules. This compound is primarily sought by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the development of fluorinated drug candidates, particularly in protease inhibitor and kinase inhibitor research.
• Agrochemical Synthesis: Used in the production of advanced, fluorinated pesticides and herbicides, where the fluorine atoms enhance biological activity and stability.
• Material Science Research: Serves as a monomer or precursor for specialty polymers and liquid crystals with unique electronic or optical properties.
• Organic Synthesis Building Block: Employed in cross-coupling reactions, nucleophilic substitutions, and other transformations to introduce the difluoroacetate group into complex molecular frameworks.
• Fluorine Chemistry Studies: A valuable reagent for academic and industrial research exploring new methodologies in fluoroorganic chemistry.

Basic Information

Product Name	Ethyl 2,2-Difluoro-2-(4-Nitrophenyl)Acetate
CAS No.	243656-25-9
Molecular Formula	C10H9F2NO4
Molecular Weight	245.18 g/mol
Synonyms	Ethyl 4-Nitro-α,α-difluorophenylacetate; 2,2-Difluoro-2-(4-nitrophenyl)acetic Acid Ethyl Ester; Ethyl (4-Nitrophenyl)difluoroacetate; 4-Nitro-α,α-difluorobenzeneacetic Acid Ethyl Ester; Acetic acid, 2,2-difluoro-2-(4-nitrophenyl)-, ethyl ester; Ethyl α,α-difluoro-4-nitrobenzeneacetate
EINECS	Contact for details

Quality Control

Our Ethyl 2,2-Difluoro-2-(4-Nitrophenyl)Acetate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistent performance. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.