Description

N1-(2,3,4-Trifluorophenyl)-2-Chloroacetamide is a specialized fluorinated acetamide derivative, serving as a critical building block in advanced organic synthesis. Its molecular structure, featuring a trifluorophenyl group and a reactive chloroacetamide moiety, makes it a valuable intermediate for constructing complex molecules with tailored properties. This compound is primarily utilized by research institutions and industrial R&D departments in the pharmaceutical and agrochemical sectors for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and infectious diseases.
• Agrochemical Research: Used in the development of next-generation herbicides and fungicides, leveraging the bioactivity of the trifluoromethylphenyl group.
• Material Science: Serves as a monomer or functionalization agent in the creation of specialty polymers and advanced materials.
• Chemical Synthesis: Versatile electrophile in organic reactions, including nucleophilic substitution and cross-coupling, for constructing complex heterocycles.
• Life Science Research: Employed as a biochemical tool or probe in medicinal chemistry programs for structure-activity relationship (SAR) studies.

Basic Information

Product Name	N1-(2,3,4-Trifluorophenyl)-2-Chloroacetamide
CAS No.	243644-03-3
Molecular Formula	C8H5ClF3NO
Molecular Weight	231.58 g/mol
Synonyms	2-Chloro-N-(2,3,4-trifluorophenyl)acetamide; 2-Chloro-2',3',4'-trifluoroacetanilide; N-(2,3,4-Trifluorophenyl)chloroacetamide; 2-Chloro-N-(2,3,4-trifluorophenyl)ethanamide; Acetamide, 2-chloro-N-(2,3,4-trifluorophenyl)-; 243644-03-3; 2-Chloro-2,3,4-trifluoroacetanilide
EINECS	Contact for details

Quality Control

Our N1-(2,3,4-Trifluorophenyl)-2-Chloroacetamide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and development applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.