Description

5-Fluoro-2-(trifluoromethyl)phenylacetonitrile is a high-value, multi-functional aromatic nitrile building block characterized by its unique combination of fluorine and trifluoromethyl substituents. This compound is essential for advanced organic synthesis, offering significant utility in modulating the lipophilicity, metabolic stability, and binding affinity of target molecules. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in oncology, CNS, and antiviral research.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides where the fluorine motifs enhance biological activity.
• Liquid Crystal & OLED Materials: Serves as a precursor in the synthesis of fluorinated compounds for electronic display and lighting applications.
• Functional Material Development: Employed in creating specialty polymers, coatings, and advanced organic frameworks with tailored properties.
• Chemical Research & Development: A versatile building block for exploring new reaction pathways and creating compound libraries in medicinal and process chemistry.

Basic Information

Product Name	5-Fluoro-2-(Trifluoromethyl)Phenylacetonitrile
CAS No.	242812-09-5
Molecular Formula	C9H5F4N
Molecular Weight	203.14 g/mol
Synonyms	2-(5-Fluoro-2-(trifluoromethyl)phenyl)acetonitrile; (5-Fluoro-2-(trifluoromethyl)phenyl)acetonitrile; 5-Fluoro-α-(trifluoromethyl)phenylacetonitrile; 242812-09-5; 5-Fluoro-2-trifluoromethylphenylacetonitrile; 2-Acetonitrile, 5-fluoro-α,α,α-trifluoro-o-tolunitrile; α-(5-Fluoro-2-(trifluoromethyl)phenyl)acetonitrile
EINECS	Contact for details

Quality Control

Our production of 5-Fluoro-2-(trifluoromethyl)phenylacetonitrile adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality system is designed to support cGMP and ISO standards for reliable supply to regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases, strong oxidizing agents, and reducing agents. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.