Description

Ziprasidone Hydrochloride is a high-purity active pharmaceutical ingredient (API) critical for the formulation of modern antipsychotic medications. Its primary value lies in its role as the key therapeutic component in treatments for schizophrenia and bipolar disorder, offering reliable efficacy and quality for pharmaceutical manufacturers. This compound is essential for R&D laboratories, generic drug producers, and finished dosage formulators in the global pharmaceutical industry. Consistent quality and reliable supply are paramount for ensuring the safety and effectiveness of the final medicinal products.

Application

• Pharmaceutical API: Primary use as the active ingredient in the manufacture of antipsychotic tablets and capsules.
• Generic Drug Development: Serves as a reference standard and raw material for generic pharmaceutical companies.
• Research & Development: Used in preclinical and clinical studies for neurological and psychiatric disorders.
• Finished Dosage Formulation: Incorporated into solid oral dosage forms requiring precise and stable API quality.
• Analytical Reference Standard: Employed in quality control laboratories for HPLC, assay, and impurity profiling.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for commercial-scale production.

Basic Information

Product Name	Ziprasidone Hydrochloride
CAS No.	241799-10-0
Molecular Formula	C21H22Cl2N4OS • HCl
Molecular Weight	467.85 g/mol
Synonyms	Ziprasidone HCl; 5-[2-[4-(1,2-Benzisothiazol-3-yl)-1-piperazinyl]ethyl]-6-chloro-1,3-dihydro-2H-indol-2-one hydrochloride; Zeldox; Geodon (Brand Name); CP-88059; 1,2-Benzisothiazole, 3-[4-(2-(6-chloro-2-oxo-1,3-dihydro-3H-indol-3-yl)ethyl]-1-piperazinyl]-, hydrochloride (1:1)
EINECS	Contact for details

Quality Control

Our Ziprasidone Hydrochloride is manufactured under strict quality management systems, targeting compliance with ICH Q7 guidelines and current Good Manufacturing Practices (cGMP). Each batch undergoes comprehensive analytical testing, including identification, assay, impurity profile, and residual solvent analysis, to ensure it meets stringent pharmaceutical-grade specifications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming purity, safety, and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 1.0% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.