Description

2-Methoxy-5-Trifluoromethylphenylboronic Acid is a high-purity, multi-functional boronic acid derivative that serves as a critical building block in modern synthetic chemistry. Its value lies in enabling precise carbon-carbon bond formation via the Suzuki-Miyaura cross-coupling reaction, a cornerstone of pharmaceutical and advanced materials development. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who require reliable, high-quality intermediates for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules containing trifluoromethyl and methoxy-substituted aromatic systems.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides where the unique trifluoromethyl group enhances biological activity and stability.
• Material Science: Employed in the creation of organic electronic materials, such as OLED (Organic Light-Emitting Diode) emitters and charge transport materials.
• Ligand & Catalyst Development: Serves as a starting material for synthesizing specialized ligands used in homogeneous catalysis.
• Chemical Research: A versatile reagent in academic and industrial R&D for exploring new synthetic pathways and creating compound libraries.
• Liquid Crystal & Polymer Chemistry: Used to introduce specific aromatic units into polymers and liquid crystal molecules to tailor their physical properties.

Basic Information

Product Name	2-Methoxy-5-Trifluoromethylphenylboronic Acid
CAS No.	240139-82-6
Molecular Formula	C8H8BF3O3
Molecular Weight	219.96 g/mol
Synonyms	(2-Methoxy-5-(trifluoromethyl)phenyl)boronic Acid; 2-Methoxy-5-(trifluoromethyl)benzeneboronic Acid; 5-Trifluoromethyl-2-methoxyphenylboronic Acid; 2-Methoxy-alpha,alpha,α-trifluoro-m-tolylboronic Acid; Boronic acid, B-[2-methoxy-5-(trifluoromethyl)phenyl]-; 2-Methoxy-5-trifluoromethylbenzeneboronic Acid; (2-Methoxy-5-trifluoromethylphenyl)boronic Acid
EINECS	Contact for details

Quality Control

Our 2-Methoxy-5-Trifluoromethylphenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and batch-to-batch consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality parameters. Our production adheres to cGMP principles where applicable, ensuring the material meets the stringent requirements for pharmaceutical and advanced chemical synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere such as nitrogen or argon.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.