Description

3-Chloro-2-(trifluoromethyl)-2-iodo-1,1,1-trifluoropropane is a highly fluorinated and halogenated organic compound, distinguished by its unique combination of chlorine, iodine, and multiple trifluoromethyl groups. This structure makes it a valuable and versatile building block and intermediate in advanced chemical synthesis, particularly for introducing fluorine-containing motifs. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients with enhanced properties.

Application

• Pharmaceutical Intermediate: A key synthon for the development of fluorinated drug candidates, where fluorine atoms can improve metabolic stability, bioavailability, and binding affinity.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, leveraging the fluorine and iodine atoms for unique biological activity.
• Material Science Research: Serves as a precursor for specialty fluoropolymers, liquid crystals, or electronic materials requiring specific halogen and fluorine content.
• Organic Synthesis Building Block: The iodine and chlorine atoms provide handles for further cross-coupling reactions (e.g., Suzuki, Sonogashira) and nucleophilic substitutions, enabling complex molecular architecture.
• Fluorination Reagent Precursor: Can be utilized to generate reagents or catalysts used in introducing trifluoromethyl groups into other organic molecules.

Basic Information

Product Name	3-Chloro-2-(trifluoromethyl)-2-iodo-1,1,1-trifluoropropane
CAS No.	240122-22-9
Molecular Formula	C4ClF6I
Molecular Weight	320.39 g/mol
Synonyms	1,1,1-Trifluoro-3-chloro-2-iodo-2-(trifluoromethyl)propane; 2-Iodo-3-chloro-1,1,1,2-tetrafluoro-2-(trifluoromethyl)propane; 3-Chloro-1,1,1,2-tetrafluoro-2-iodo-2-(trifluoromethyl)propane; CF3CICF2CF2I (common structural shorthand); Halogenated Trifluoropropane Derivative; Perfluoroalkyl iodide-chloride intermediate
EINECS	Contact for details

Quality Control

Our production of 3-Chloro-2-(trifluoromethyl)-2-iodo-1,1,1-trifluoropropane adheres to a strict quality management system. Every batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports applications in cGMP environments and aligns with global regulatory expectations for advanced chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber-colored or stored in dark conditions.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.