Description

4,5,5,6,6,6-Hexafluoro-4-(Trifluoromethyl)Hexanoic Acid is a highly fluorinated carboxylic acid building block, valued for its unique combination of strong acidity and exceptional lipophilicity imparted by its perfluoroalkyl chain. This compound is critical for the synthesis of advanced materials and specialty chemicals where the introduction of fluorine atoms dramatically alters physical and chemical properties. It serves as a key intermediate for researchers and manufacturers in the pharmaceutical, agrochemical, and high-performance polymer industries.

Application

• Pharmaceutical Intermediate: Used in the synthesis of active pharmaceutical ingredients (APIs), particularly for introducing fluorine to enhance metabolic stability, bioavailability, and membrane permeability.
• Agrochemical Synthesis: Serves as a precursor for novel herbicides, pesticides, and fungicides, where the fluorine content improves weather resistance and biological activity.
• Fluorinated Surfactant & Polymer Production: A key monomer for creating surfactants with superior wetting properties and for synthesizing specialty fluoropolymers with high chemical and thermal resistance.
• Liquid Crystal & Electronic Materials: Employed in the development of fluorinated liquid crystals for displays and as a building block for dielectric materials and other electronic chemicals.
• Catalyst & Ligand Modification: Used to prepare fluorinated ligands for metal catalysts, potentially improving catalyst performance in specific organic transformations.
• Research & Development: A valuable tool for academic and industrial R&D in medicinal chemistry, material science, and synthetic organic chemistry exploring fluorine chemistry.

Basic Information

Product Name	4,5,5,6,6,6-Hexafluoro-4-(Trifluoromethyl)Hexanoic Acid
CAS No.	239463-95-7
Molecular Formula	C7H4F9O2
Molecular Weight	276.09 g/mol
Synonyms	4-(Trifluoromethyl)-4,5,5,6,6,6-hexafluorohexanoic acid; Perfluoro(4-methylpentanoic acid) derivative; 4-Methyl-4,5,5,6,6,6-hexafluoroperfluorohexanoic acid; 4-(Trifluoromethyl)-4,5,5,6,6,6-hexafluorocaproic acid; Hexanoic acid, 4,5,5,6,6,6-hexafluoro-4-(trifluoromethyl)-; HFTHA
EINECS	Contact for details

Quality Control

Our 4,5,5,6,6,6-Hexafluoro-4-(Trifluoromethyl)Hexanoic Acid is produced under strict quality management systems. Every batch undergoes rigorous analytical testing, including chromatography and spectroscopy, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing assay, impurity profile, and physical properties is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and a strong acid/organic solvent; ensure containers are kept tightly sealed to exclude moisture and incompatible materials. Keep away from heat, sparks, open flames, and strong bases.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.