Description

2-(Trifluoromethylthio)Phenylacetic Acid is a high-value fluorinated aromatic building block characterized by its unique phenylacetic acid core substituted with a trifluoromethylthio group. This compound is essential for the synthesis of advanced pharmaceutical intermediates and agrochemicals, where the introduction of fluorine and sulfur-containing moieties is critical for modulating biological activity, metabolic stability, and lipophilicity. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, particularly in areas requiring fluorinated bioactive molecules.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides where the CF3S- group enhances efficacy.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in catalytic systems and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of monomers or additives for advanced polymers with specific surface or electronic properties.
• Chemical Biology Probes: Useful for synthesizing molecular probes to study enzyme mechanisms or protein interactions.

Basic Information

Product Name	2-(Trifluoromethylthio)Phenylacetic Acid
CAS No.	239080-01-4
Molecular Formula	C9H7F3O2S
Molecular Weight	236.21 g/mol
Synonyms	2-[(Trifluoromethyl)sulfanyl]benzeneacetic acid; [2-(Trifluoromethylsulfanyl)phenyl]acetic acid; α-(2-(Trifluoromethylthio)phenyl)acetic acid; 2-(Trifluoromethylthio)benzeneacetic acid; (2-((Trifluoromethyl)thio)phenyl)acetic acid; Phenylacetic acid, 2-(trifluoromethylthio)-; 239080-01-4
EINECS	Contact for details

Quality Control

Our 2-(Trifluoromethylthio)Phenylacetic Acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality commitment supports applications in regulated research and development environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases, strong oxidizing agents, and heat sources. The material may be moisture-sensitive; ensure containers are sealed after use to minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.