Description

3-Fluoro-4-(Trifluoromethyl)Phenylacetic Acid is a high-value fluorinated aromatic building block essential for advanced organic synthesis. This compound matters for its unique trifluoromethyl and fluorine substituents, which impart desirable properties like enhanced metabolic stability and lipophilicity to target molecules. It is primarily needed by researchers and manufacturers in the pharmaceutical and agrochemical industries for developing new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly for CNS and anti-inflammatory targets.
• Agrochemical Synthesis: Used in the creation of advanced herbicides and pesticides, where the fluorine atoms improve biological activity and environmental persistence.
• Liquid Crystal Materials: Serves as a precursor in the synthesis of fluorinated liquid crystals for high-performance displays.
• Organic Electronics: Employed in the development of materials for organic light-emitting diodes (OLEDs) and semiconductors.
• Chemical Research: A versatile building block for Suzuki-Miyaura and other cross-coupling reactions to create complex, fluorinated biaryl structures.
• Peptide Mimetics: Used to incorporate fluorinated phenylacetic acid motifs into peptide backbones to modulate stability and receptor binding.

Basic Information

Product Name	3-Fluoro-4-(Trifluoromethyl)Phenylacetic Acid
CAS No.	238754-67-1
Molecular Formula	C9H6F4O2
Molecular Weight	222.14 g/mol
Synonyms	2-[3-Fluoro-4-(trifluoromethyl)phenyl]acetic Acid; (3-Fluoro-4-trifluoromethylphenyl)acetic Acid; α-(3-Fluoro-4-(trifluoromethyl)phenyl)acetic Acid; 3-Fluoro-4-(trifluoromethyl)benzeneacetic Acid; 4-(Trifluoromethyl)-3-fluorophenylacetic Acid; F-TFM-PAA; 238754-67-1; 3-Fluoro-α-carboxy-4-trifluoromethyltoluene
EINECS	Contact for details

Quality Control

Our 3-Fluoro-4-(Trifluoromethyl)Phenylacetic Acid is produced under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure compliance with exacting R&D and production standards. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.