Description

2-(Trifluoromethylthio)Phenylacetonitrile is a versatile fluorinated aromatic nitrile building block. This compound matters for its unique trifluoromethylthio (-SCF₃) functional group, which is highly sought after for its lipophilicity and metabolic stability in advanced molecular design. It is primarily needed by researchers and manufacturers in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key synthon for developing new drug candidates, particularly in CNS and antiviral research.
• Agrochemical Synthesis: Building block for novel pesticides and herbicides leveraging the -SCF₃ moiety for enhanced bioactivity.
• Material Science Research: Used in the development of specialty polymers and liquid crystals with unique electronic properties.
• Organic Synthesis: A versatile reagent for introducing the trifluoromethylthio group into complex molecules via cross-coupling or nucleophilic substitution reactions.
• Chemical Biology Probes: Useful in creating labeled compounds and probes for studying biological mechanisms.

Basic Information

Product Name	2-(Trifluoromethylthio)Phenylacetonitrile
CAS No.	237424-20-3
Molecular Formula	C₉H₆F₃NS
Molecular Weight	217.21 g/mol
Synonyms	2-[(Trifluoromethyl)sulfanyl]benzeneacetonitrile; (2-(Trifluoromethylthio)phenyl)acetonitrile; α-Cyano-2-(trifluoromethylthio)toluene; Benzeneacetonitrile, 2-[(trifluoromethyl)thio]-; 2-(Trifluoromethylsulfanyl)phenylacetonitrile; 2-(Trifluoromethylmercapto)phenylacetonitrile; 2-(SCF₃)Phenylacetonitrile
EINECS	Contact for details

Quality Control

Our 2-(Trifluoromethylthio)Phenylacetonitrile is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your R&D and quality assurance processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.