Description

2-Fluoro-3-(Trifluoromethyl)Cinnamic Acid is a high-value fluorinated cinnamic acid derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both fluorine and trifluoromethyl groups, imparts desirable properties such as enhanced metabolic stability and lipophilicity to target molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, especially in kinase inhibitor and anti-inflammatory agent research.
• Agrochemical Synthesis: Used in the creation of advanced herbicides and pesticides, where the fluorine atoms contribute to biological activity and environmental persistence.
• Material Science: Serves as a monomer or precursor for specialty polymers and liquid crystals with tailored optical and electronic properties.
• Chemical Research: Employed in academic and industrial R&D for studying structure-activity relationships (SAR) and fluorination effects.
• Peptide Mimetics: Incorporated into peptide analogs to enhance stability against enzymatic degradation.

Basic Information

Product Name	2-Fluoro-3-(Trifluoromethyl)Cinnamic Acid
CAS No.	237069-83-9
Molecular Formula	C₁₀H₆F₄O₂
Molecular Weight	234.15 g/mol
Synonyms	(E)-3-[2-Fluoro-3-(trifluoromethyl)phenyl]acrylic acid; 2-Fluoro-α,3-bis(trifluoromethyl)cinnamic acid; (2E)-3-[2-Fluoro-3-(trifluoromethyl)phenyl]prop-2-enoic acid; 3-(2-Fluoro-3-(trifluoromethyl)phenyl)acrylic acid; FTCA; 2-Fluoro-3-trifluoromethylcinnamic Acid
EINECS	Contact for details

Quality Control

Our 2-Fluoro-3-(Trifluoromethyl)Cinnamic Acid is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for advanced synthetic applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.