Description

1-(2,3-Difluorophenyl)Propan-1-One is a high-purity fluorinated aromatic ketone building block of significant interest in advanced organic synthesis. Its value lies in the strategic placement of fluorine atoms on the phenyl ring, which can dramatically influence the electronic properties, metabolic stability, and binding affinity of final target molecules. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, particularly in central nervous system (CNS) and anti-inflammatory therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and pesticides, where the difluorophenyl moiety enhances biological activity.
• Liquid Crystal & OLED Material Precursor: Serves as a building block for fluorinated organic electronic materials due to its ability to modify polarity and intermolecular interactions.
• Organic Synthesis Building Block: Employed in cross-coupling reactions, Grignard reactions, and reductions to introduce the 2,3-difluorophenylpropyl fragment into more complex architectures.
• Chemical Research & Development: Essential for academic and industrial labs exploring structure-activity relationships (SAR) in medicinal and materials chemistry.

Basic Information

Product Name	1-(2,3-Difluorophenyl)Propan-1-One
CAS No.	236754-63-5
Molecular Formula	C9H8F2O
Molecular Weight	170.16 g/mol
Synonyms	2,3-Difluoropropiophenone; 1-Propanone, 1-(2,3-difluorophenyl)-; 2',3'-Difluoropropiophenone; 2,3-Difluoro-1-phenyl-1-propanone; 1-(2,3-Difluorophenyl)-1-propanone; Propiophenone, 2',3'-difluoro-; 2,3-Difluorophenyl propyl ketone
EINECS	Contact for details

Quality Control

Our 1-(2,3-Difluorophenyl)Propan-1-One is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our commitment to consistent quality and traceability supports your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.