Description

1,1,1-Trifluoro-2,2,2-Tris(Dimethylamino)-Ethane is a specialized organofluorine compound featuring a unique trifluoroethyl core substituted with three dimethylamino groups. This structure makes it a valuable reagent and building block in advanced chemical synthesis, particularly for introducing fluorine-containing motifs. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors. Its properties are leveraged in the creation of novel compounds with enhanced biological activity or specific physical characteristics.

Application

• Pharmaceutical Intermediate: Serves as a key fluorinated synthon in the research and development of new active pharmaceutical ingredients (APIs), especially for introducing the trifluoroethyl group.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides where fluorine atoms improve efficacy and environmental stability.
• Ligand Precursor in Catalysis: Acts as a starting material for synthesizing sophisticated nitrogen-donor ligands used in transition metal catalysis.
• Material Science Research: Employed in the development of fluorinated polymers, coatings, and electronic materials to modify surface properties and stability.
• Organic Synthesis Building Block: Utilized in academic and industrial R&D for constructing complex molecules via reactions at the amino or fluoro sites.

Basic Information

Product Name	1,1,1-Trifluoro-2,2,2-Tris(Dimethylamino)-Ethane
CAS No.	234451-82-2
Molecular Formula	C8H18F3N3
Molecular Weight	213.25 g/mol
Synonyms	1,1,1-Trifluoro-2,2,2-tris(dimethylamino)ethane; Tris(dimethylamino)(trifluoromethyl)methane; 2,2,2-Trifluoro-1,1,1-tris(dimethylamino)ethane; N,N,N',N',N'',N''-Hexamethyl-2,2,2-trifluoroethanetriamine; TFDE; Trifluoroethylidene tris(dimethylamine)
EINECS	Contact for details

Quality Control

Our production of 1,1,1-Trifluoro-2,2,2-Tris(Dimethylamino)-Ethane adheres to stringent internal quality standards to ensure batch-to-batch consistency and reliability for your synthetic processes. Each lot is analyzed using advanced techniques including NMR, GC, and HPLC to verify identity and purity. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from strong acids and strong bases.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.