Description

2-Bromo-3,4,4,4-Tetrafluoro-3-Trifluoromethyl-1-Butene is a highly fluorinated organic bromide building block of significant interest in advanced chemical synthesis. This compound matters for its unique molecular architecture, which combines a reactive bromoalkene moiety with a perfluorinated side chain, enabling precise introduction of fluorinated segments into target molecules. It is primarily needed by R&D chemists and process development teams in the pharmaceutical, agrochemical, and specialty materials sectors for creating novel compounds with tailored properties.

Application

• Pharmaceutical Intermediate: Serves as a key synthon for introducing fluorinated alkyl groups into active pharmaceutical ingredients (APIs) to modulate lipophilicity, metabolic stability, and bioavailability.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, insecticides, and fungicides where the fluorinated moiety can enhance biological activity and environmental persistence.
• Fluorinated Polymer & Material Science: Acts as a monomer or modifier in the synthesis of specialty polymers, coatings, and elastomers to impart oil repellency, chemical resistance, and low surface energy.
• Liquid Crystal & Electronic Chemicals: Employed in the development of fluorinated components for liquid crystal displays (LCDs) and dielectric fluids.
• Organic Synthesis Building Block: Utilized in cross-coupling reactions, nucleophilic substitutions, and cycloadditions to construct complex, fluorinated molecular frameworks in academic and industrial research.
• Refrigerant & Propellant Research: Investigated as a potential component or precursor in next-generation fluorocarbon blends due to its specific volatility profile.

Basic Information

Product Name	2-Bromo-3,4,4,4-Tetrafluoro-3-Trifluoromethyl-1-Butene
CAS No.	234443-24-4
Molecular Formula	C5H2BrF7
Molecular Weight	274.96 g/mol
Synonyms	1-Butene, 2-bromo-3,4,4,4-tetrafluoro-3-(trifluoromethyl)-; 2-Bromo-3,4,4,4-tetrafluoro-3-(trifluoromethyl)but-1-ene; 3,4,4,4-Tetrafluoro-3-trifluoromethyl-2-bromo-1-butene; 2-Bromo-1,1,1,2,3,3,3-heptafluoro-2-methylpropane (tautomeric form); Perfluoroisobutylene bromide derivative; HFIB-Br; Heptafluoroisobutenyl bromide
EINECS	Contact for details

Quality Control

Our 2-Bromo-3,4,4,4-Tetrafluoro-3-Trifluoromethyl-1-Butene is produced and handled under strict quality management protocols. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the precise requirements of advanced synthetic applications. Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data (GC, HPLC, NMR) are provided to guarantee traceability and compliance with your internal specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from heat sources and incompatible materials such as strong bases and reducing agents. Due to its high volatility, ensure containers are properly sealed and stored upright. Recommended storage temperature: 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to reference spectrum
Purity (GC)	≥ 97.0%
Purity (HPLC)	≥ 96.5%
Water Content (KF)	≤ 0.1%
Density (at 20°C)	~1.8 g/mL
Boiling Point	~85-90°C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.