Description

1-Acetyl-3-[1-(Heptafluoropropoxy)-1,2,2,2-Tetrafluoroethyl]-5-Methyl-1H-Pyrazole is a high-value, fluorinated pyrazole derivative characterized by its unique heptafluoropropoxy and tetrafluoroethyl substituents. This compound is a critical advanced intermediate for the synthesis of complex molecules, offering significant advantages in tuning lipophilicity, metabolic stability, and electronic properties. It is primarily sought after by R&D and process development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key building block for the development of new drug candidates, particularly in medicinal chemistry programs targeting improved bioavailability and patent life.
• Agrochemical Synthesis: Used in the research and production of next-generation herbicides, fungicides, and insecticides where fluorine incorporation enhances biological activity and environmental persistence.
• Material Science Research: Acts as a precursor for specialty polymers, coatings, and liquid crystals that require specific fluorinated segments for enhanced chemical resistance or optical properties.
• Organic Electronics: Investigated as a component in the synthesis of novel organic semiconductors and electron-transport materials due to its electron-withdrawing fluorinated groups.
• Chemical Biology Probes: Utilized in the design of fluorinated probes and tags for advanced imaging and diagnostic applications.

Basic Information

Product Name	1-Acetyl-3-[1-(Heptafluoropropoxy)-1,2,2,2-Tetrafluoroethyl]-5-Methyl-1H-Pyrazole
CAS No.	231301-28-3
Molecular Formula	C11H7F11N2O2
Molecular Weight	408.17 g/mol
Synonyms	1-Acetyl-5-methyl-3-[1,2,2,2-tetrafluoro-1-(heptafluoropropoxy)ethyl]-1H-pyrazole; 1H-Pyrazole, 1-acetyl-3-[1,2,2,2-tetrafluoro-1-(heptafluoropropoxy)ethyl]-5-methyl-; 1-Acetyl-3-(1-heptafluoropropoxy-1,2,2,2-tetrafluoroethyl)-5-methyl-1H-pyrazole; Fluorinated Pyrazole Acetamide Derivative; Heptafluoropropoxy Tetrafluoroethyl Pyrazole Intermediate
EINECS	Contact for details

Quality Control

Every batch of our 1-Acetyl-3-[1-(Heptafluoropropoxy)-1,2,2,2-Tetrafluoroethyl]-5-Methyl-1H-Pyrazole is manufactured under strict quality management systems. We employ advanced analytical techniques including HPLC, GC, NMR, and MS to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.