Description

5-Fluoro-2-(trifluoromethyl)benzylamine is a high-value fluorinated aromatic amine building block, essential for the synthesis of advanced chemical entities. Its unique structure, featuring both fluorine and trifluoromethyl substituents, imparts significant lipophilicity and metabolic stability to target molecules, making it a critical intermediate for research and development. This compound is primarily sought after by pharmaceutical, agrochemical, and advanced material scientists for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the development of active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) drugs, kinase inhibitors, and anti-inflammatory agents.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides, where the fluorine atoms enhance biological activity and environmental persistence.
• Liquid Crystal & OLED Materials: Serves as a building block for fluorinated components in electronic display materials and organic light-emitting diodes (OLEDs).
• Polymer & Resin Modifier: Incorporated into specialty polymers to alter surface properties, increase chemical resistance, and improve durability.
• Chemical Research & Development: Employed in academic and industrial R&D for exploring new reactions and creating compound libraries for high-throughput screening.
• Dye & Pigment Intermediate: Used in the synthesis of specialized fluorinated dyes and pigments with unique color fastness and stability properties.

Basic Information

Item	Detail
Product Name	5-Fluoro-2-(Trifluoromethyl)Benzylamine
CAS No.	231291-14-8
Molecular Formula	C8H7F4N
Molecular Weight	193.14 g/mol
Synonyms	α-(Trifluoromethyl)-5-fluorobenzylamine; (5-Fluoro-2-(trifluoromethyl)phenyl)methanamine; 1-(5-Fluoro-2-(trifluoromethyl)phenyl)methanamine; 2-(Aminomethyl)-1-fluoro-4-(trifluoromethyl)benzene; 5-Fluoro-α-(trifluoromethyl)benzylamine; 5-Fluoro-2-trifluoromethylbenzylamine; 2-(Trifluoromethyl)-5-fluorobenzylamine
EINECS	Contact for details

Quality Control

Our 5-Fluoro-2-(trifluoromethyl)benzylamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.