Description

n-Methoxy-n-Methyl-2-Thiophenecarboxamide is a specialized organic compound belonging to the class of Weinreb amides, which are pivotal synthetic intermediates in modern organic chemistry. This compound is highly valued for its role as a versatile building block, enabling the controlled synthesis of ketones and aldehydes from various nucleophiles. It is primarily sought after by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing complex thiophene-containing molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) containing the thiophene moiety, which is common in drugs targeting CNS disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides where the thiophene ring contributes to biological activity.
• Material Science Research: Serves as a building block for creating organic semiconductors, conductive polymers, and non-linear optical materials due to the electron-rich nature of thiophene.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes and inhibitors for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A critical reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing high-value, low-volume specialty chemicals.

Basic Information

Product Name	n-Methoxy-n-Methyl-2-Thiophenecarboxamide
CAS No.	229970-94-9
Molecular Formula	C8H11NO2S
Molecular Weight	185.24 g/mol
Synonyms	2-Thiophenecarboxylic acid, N-methoxy-N-methylamide; N-Methoxy-N-methylthiophene-2-carboxamide; 2-(N-Methoxy-N-methylcarbamoyl)thiophene; N-Methoxy-N-methyl-2-thiophenecarboxamide; Weinreb amide of 2-thiophenecarboxylic acid; Thiophene-2-Weinreb amide; N-Methoxy-N-methyl-2-thenamide
EINECS	Contact for details

Quality Control

Our n-Methoxy-n-Methyl-2-Thiophenecarboxamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.