Description

1-Bromo-2-Nitro-4,5-Di(Trifluoromethyl)Benzene is a high-value, multi-functional aromatic building block characterized by its bromo, nitro, and trifluoromethyl substituents. This compound is essential for introducing specific steric and electronic properties into target molecules, enabling advanced material and pharmaceutical research. It is primarily sought after by R&D chemists and process development scientists in the agrochemical, pharmaceutical, and specialty materials industries for synthesizing novel active ingredients and functional intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those requiring fluorinated aromatic systems for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides where the trifluoromethyl groups contribute to lipophilicity and biological activity.
• Liquid Crystal & OLED Materials: Serves as a building block for fluorinated components in electronic display materials and organic light-emitting diodes (OLEDs).
• Polymer & Resin Modification: Incorporated into specialty polymers to impart unique chemical resistance, thermal stability, or specific optical properties.
• Cross-Coupling Reactions: The bromo substituent makes it an excellent substrate for palladium-catalyzed reactions like Suzuki, Heck, and Sonogashira couplings for carbon-carbon bond formation.
• Chemical Research & Development: A versatile reagent for exploring new synthetic pathways and creating novel fluorinated compounds in academic and industrial R&D settings.

Basic Information

Product Name	1-Bromo-2-Nitro-4,5-Di(Trifluoromethyl)Benzene
CAS No.	229957-08-8
Molecular Formula	C8H2BrF6NO2
Molecular Weight	313.99 g/mol
Synonyms	2-Nitro-1-bromo-4,5-bis(trifluoromethyl)benzene; 4,5-Bis(trifluoromethyl)-2-nitro-1-bromobenzene; 1-Bromo-2-nitro-4,5-bis(trifluoromethyl)benzene; Benzene, 1-bromo-2-nitro-4,5-bis(trifluoromethyl)-; 229957-08-8; 4,5-Di(trifluoromethyl)-2-nitro-1-bromobenzene
EINECS	Contact for details

Quality Control

Every batch of 1-Bromo-2-Nitro-4,5-Di(Trifluoromethyl)Benzene is manufactured and analyzed under strict quality management protocols to ensure consistency and purity for critical applications. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids and organic solvents. Recommended storage temperature is between 15°C and 25°C. Keep container tightly sealed when not in use to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.