Description

7-Trifluoromethyl-Benzo[D]Isoxazol-3-Ylamine is a high-value, fluorinated heterocyclic amine building block essential for advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel pharmaceuticals and agrochemicals, where the trifluoromethyl group imparts desirable metabolic stability and lipophilicity. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries seeking to incorporate this privileged scaffold into new active molecules.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of potential drug candidates, particularly in central nervous system (CNS) and anti-infective research.
• Agrochemical Synthesis: Used in the development of new-generation herbicides, fungicides, and insecticides, leveraging the biological activity of the isoxazole ring.
• Material Science Research: Serves as a precursor for functionalized polymers or liquid crystals where the fluorine atoms can modify material properties.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme mechanisms and biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific custom synthesis projects.

Basic Information

Product Name	7-Trifluoromethyl-Benzo[D]Isoxazol-3-Ylamine
CAS No.	229623-52-3
Molecular Formula	C8H5F3N2O
Molecular Weight	202.14 g/mol
Synonyms	3-Amino-7-(trifluoromethyl)-1,2-benzisoxazole; 7-(Trifluoromethyl)-1,2-benzisoxazol-3-amine; 7-Trifluoromethyl-1,2-benzisoxazol-3-ylamine; 7-Trifluoromethylbenzo[d]isoxazol-3-amine; 3-Amino-7-trifluoromethylbenzo[d]isoxazole; 229623-52-3; 7-Trifluoromethyl benzisoxazol-3-amine
EINECS	Contact for details

Quality Control

Our 7-Trifluoromethyl-Benzo[D]Isoxazol-3-Ylamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.