Description

4-[2-[[(6R,7R)-7-Amino-2-Carboxy-8-Oxo-5-Thia-1-Azabicyclo[4.2.0]Oct-2-En-3-Yl]Thio]-4-Thiazolyl]-1-Methyl-Pyridinium Chloride is a key advanced pharmaceutical intermediate, specifically a cephalosporin derivative, valued for its role in the synthesis of modern antibiotics. Its precise stereochemistry and functional groups make it an essential building block for developing active pharmaceutical ingredients (APIs) with targeted efficacy. This compound is primarily required by pharmaceutical manufacturers and research institutions engaged in the development and production of next-generation antibacterial agents.

Application

• Active Pharmaceutical Ingredient (API) Synthesis: Critical intermediate in the production of advanced cephalosporin-class antibiotics.
• Pharmaceutical Research & Development: Used as a key scaffold in medicinal chemistry for designing novel antibacterial compounds.
• Process Chemistry & Scale-Up: Serves as a validated intermediate for pilot plant and commercial-scale manufacturing processes.
• Reference Standard: Employed as a high-purity analytical standard for quality control and regulatory submissions.
• Antibacterial Agent Development: Fundamental component in creating new drugs to combat resistant bacterial strains.

Basic Information

Product Name	4-[2-[[(6R,7R)-7-Amino-2-Carboxy-8-Oxo-5-Thia-1-Azabicyclo[4.2.0]Oct-2-En-3-Yl]Thio]-4-Thiazolyl]-1-Methyl-Pyridinium Chloride
CAS No.	229016-75-5
Molecular Formula	C18H18ClN5O4S3
Molecular Weight	524.01 g/mol
Synonyms	7-Amino-3-[(4-(1-methylpyridinium-4-yl)thiazol-2-yl)thio]ceph-3-em-4-carboxylic acid chloride; Cephalosporin derivative intermediate; (6R,7R)-7-Amino-3-[[4-(1-methyl-4-pyridinio)-2-thiazolyl]thio]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid chloride; 4-[2-[[(6R,7R)-7-Amino-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]thio]-4-thiazolyl]-1-methylpyridinium chloride; Antibiotic intermediate 229016-75-5; 1-Methyl-4-[2-[[(6R,7R)-7-amino-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]thio]-4-thiazolyl]pyridinium chloride
EINECS	Contact for details

Quality Control

Our 4-[2-[[(6R,7R)-7-Amino-2-Carboxy-8-Oxo-5-Thia-1-Azabicyclo[4.2.0]Oct-2-En-3-Yl]Thio]-4-Thiazolyl]-1-Methyl-Pyridinium Chloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting full specifications are provided to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.