Description

3-Hexyn-2-One, 5-Hydroxy-, (5S)- (9Ci) is a chiral, hydroxylated alkyne ketone, a specialized building block in fine chemical synthesis. Its unique structure, featuring both a terminal alkyne and a stereogenic center, makes it a valuable precursor for constructing complex molecular architectures. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and advanced intermediates.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of potential drug candidates, particularly in medicinal chemistry programs targeting specific biological pathways.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators that require stereochemical precision.
• Ligand and Catalyst Development: Serves as a precursor for creating novel chiral ligands and organometallic catalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of specialized monomers or functionalized molecules for advanced polymeric materials.
• Academic & Industrial R&D: A versatile tool for methodological development in organic synthesis, including click chemistry and cross-coupling reactions.

Basic Information

Product Name	3-Hexyn-2-One, 5-Hydroxy-, (5S)- (9Ci)
CAS No.	229015-36-5
Molecular Formula	C₆H₈O₂
Molecular Weight	112.13 g/mol
Synonyms	(5S)-5-Hydroxy-3-hexyn-2-one; (S)-5-Hydroxy-3-hexyn-2-one; 5-Hydroxy-3-hexyn-2-one, (5S)-; 3-Hexyn-2-one, 5-hydroxy-, (5S)-; (S)-5-Hydroxyhex-3-yn-2-one; 229015-36-5; (5S)-5-Hydroxyhex-3-yn-2-one
EINECS	Contact for details

Quality Control

Our 3-Hexyn-2-One, 5-Hydroxy-, (5S)- (9Ci) is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure high chemical and enantiomeric purity suitable for demanding research and development applications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (typically 15-25°C). This material is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.