Description

1-Acetamido-2,3,4,6-Tetra-o-Acetyl-1-Deoxy-β-D-Galactopyranosyl Cyanide is a sophisticated, fully protected glycosyl donor derivative, a key intermediate in the synthesis of complex oligosaccharides and glycoconjugates. Its value lies in providing a reactive cyanide leaving group at the anomeric center, enabling stereoselective glycosylation reactions critical for constructing biologically relevant carbohydrate structures. This high-purity building block is essential for researchers and manufacturers in pharmaceutical development, chemical biology, and advanced material science, particularly for creating glycomimetics, vaccines, and diagnostic probes.

Application

• Glycosylation Reagent: A key building block for the stereoselective synthesis of β-linked galactosamine-containing oligosaccharides and glycoconjugates.
• Pharmaceutical Intermediates: Critical for the research and production of novel glycopeptide antibiotics, anticancer agents, and other therapeutic molecules targeting carbohydrate-mediated biological processes.
• Chemical Biology Probes: Used to create labeled or modified carbohydrates for studying glycan-protein interactions, enzyme mechanisms, and cell surface recognition events.
• Vaccine Adjuvant Development: Serves as a precursor for synthesizing complex carbohydrate antigens used in conjugate vaccine formulations.
• Material Science: Enables the creation of functionalized surfaces and polymers with specific carbohydrate motifs for biosensing and biomaterial applications.
• Process Development: A high-quality starting material for scaling up the production of defined carbohydrate sequences under Good Manufacturing Practice (GMP) conditions.

Basic Information

Product Name	1-Acetamido-2,3,4,6-Tetra-o-Acetyl-1-Deoxy-β-D-Galactopyranosyl Cyanide
CAS No.	229015-12-7
Molecular Formula	C₁₇H₂₂N₂O₁₀
Molecular Weight	414.37 g/mol
Synonyms	2-Acetamido-2-deoxy-β-D-galactopyranosyl Cyanide Tetraacetate; Peracetylated Galactosaminyl Cyanide; 2-Acetamido-3,4,6-tri-O-acetyl-2-deoxy-β-D-galactopyranosyl Cyanide; 1-Cyano-2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-β-D-galactopyranose; N-Acetyl-β-D-galactosaminyl Cyanide Tetraacetate; Glycosyl Cyanide Donor (GalNAc); β-D-GalNAc(CN) Tetraacetate
EINECS	Contact for details

Quality Control

Our 1-Acetamido-2,3,4,6-Tetra-o-Acetyl-1-Deoxy-β-D-Galactopyranosyl Cyanide is produced under stringent quality systems to ensure batch-to-batch consistency and high chemical purity suitable for sensitive synthetic applications. Each lot undergoes comprehensive analytical characterization, including NMR (¹H and ¹³C), HPLC, and mass spectrometry, to confirm identity, anomeric purity, and absence of critical impurities. A detailed Certificate of Analysis (COA) documenting all specifications is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic); ensure the container is sealed under an inert atmosphere after each use to maintain stability and prevent decomposition. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Anomeric Purity (β-isomer)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.