Description

Cyclopentanecarboxamide, n-Hydroxy-2-(Hydroxymethyl)-, (1S,2R)- (9Ci) is a high-purity, stereochemically defined chiral building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel pharmaceutical actives, particularly those targeting complex biological pathways. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to incorporate its unique functionalized cyclopentane scaffold into new molecular entities.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral synthon in the research and synthesis of new drug candidates, especially for central nervous system (CNS) and metabolic disorder targets.
• Protease Inhibitor Development: Utilized in constructing the core structures of inhibitors for various enzymes, leveraging the hydroxamic acid and hydroxymethyl functional groups.
• Agrochemical Active Ingredient Synthesis: Acts as a building block for novel herbicides, fungicides, or insecticides that require a specific three-dimensional configuration for optimal activity.
• Ligand for Catalysis: Employed in the development of chiral ligands or organocatalysts for asymmetric synthesis, benefiting from its multiple coordination sites.
• Bioconjugation & Probe Synthesis: Used in medicinal chemistry to create chemical probes or for bioconjugation strategies due to its reactive hydroxylamine derivative potential.
• Academic & Contract Research: Essential for universities and CROs (Contract Research Organizations) conducting fundamental research in synthetic methodology and medicinal chemistry.

Basic Information

Product Name	Cyclopentanecarboxamide, n-Hydroxy-2-(Hydroxymethyl)-, (1S,2R)- (9Ci)
CAS No.	228422-19-3
Molecular Formula	C7H13NO3
Molecular Weight	159.18 g/mol
Synonyms	(1S,2R)-N-Hydroxy-2-(hydroxymethyl)cyclopentanecarboxamide; (1S,2R)-2-(Hydroxymethyl)-N-hydroxycyclopentanecarboxamide; (1S,2R)-2-Hydroxymethylcyclopentanehydroxamic acid; N-Hydroxy-2-(hydroxymethyl)cyclopentanecarboxamide (1S,2R)-; L-erythro-N-Hydroxy-2-(hydroxymethyl)cyclopentanecarboxamide; A chiral cyclopentane hydroxamic acid derivative; CAS 228422-19-3
EINECS	Contact for details

Quality Control

Our Cyclopentanecarboxamide, n-Hydroxy-2-(Hydroxymethyl)-, (1S,2R)- (9Ci) is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity, suitable for demanding R&D and scale-up applications. All batches are characterized by advanced analytical techniques including HPLC, NMR, and chiral analysis. Certificates of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles are provided with every shipment to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% e.e.
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.