Description

4-Bromo-2-Trifluoromethyl-Biphenyl is a high-value halogenated biphenyl derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its molecular structure, featuring both bromine and trifluoromethyl substituents, makes it an essential building block for constructing complex molecules with tailored electronic and steric properties. This compound is primarily utilized by research institutions and industrial R&D departments in the pharmaceutical and agrochemical sectors for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a core structure in the production of advanced electronic materials for displays and lighting, leveraging its rigid biphenyl core and halogen atoms.
• Ligand & Catalyst Development: Employed in organometallic chemistry to create specialized ligands for transition metal catalysts used in cross-coupling reactions.
• Chemical Research & Development: A versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Polymer Modification: Acts as a monomer or functionalizing agent to introduce aromaticity and halogen functionality into polymer backbones for specialty plastics.

Basic Information

Product Name	4-Bromo-2-Trifluoromethyl-Biphenyl
CAS No.	227306-19-6
Molecular Formula	C₁₃H₈BrF₃
Molecular Weight	301.11 g/mol
Synonyms	2-(Trifluoromethyl)-4-bromobiphenyl; 4'-Bromo-2'-(trifluoromethyl)biphenyl; [1,1'-Biphenyl]-4-bromo-2-(trifluoromethyl)-; 4-Bromo-2-(trifluoromethyl)-1,1'-biphenyl; 4-Bromo-2-(trifluoromethyl)biphenyl; 2-Trifluoromethyl-4-bromobiphenyl; Biphenyl, 4-bromo-2-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our 4-Bromo-2-Trifluoromethyl-Biphenyl is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, GC for residual solvents, and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and industrial synthesis. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.