Description

Pentanoic Acid, 4-Fluoro-4-Methyl-3-Oxo-, Ethyl Ester is a specialized fluorinated keto-ester building block of significant interest in advanced organic synthesis. Its molecular architecture, featuring both a fluorine atom and a β-ketoester moiety, makes it a versatile precursor for constructing complex molecules with tailored properties. This compound is primarily sought by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the synthesis of fluorinated active pharmaceutical ingredients (APIs), leveraging the fluorine atom to modulate bioavailability and metabolic stability.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and pesticides where the introduction of fluorine can enhance biological activity and environmental persistence.
• Advanced Material Synthesis: Acts as a monomer or precursor for fluorinated polymers and specialty chemicals with unique surface properties, such as oil and water repellency.
• Organic Synthesis Building Block: Utilized in Claisen condensations, Michael additions, and other carbon-carbon bond-forming reactions to create complex, fluorinated molecular scaffolds.
• Ligand and Catalyst Development: Employed in the preparation of fluorinated ligands for asymmetric catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	Pentanoic Acid, 4-Fluoro-4-Methyl-3-Oxo-, Ethyl Ester
CAS No.	227184-06-7
Molecular Formula	C8H13FO3
Molecular Weight	176.18 g/mol
Synonyms	Ethyl 4-Fluoro-4-methyl-3-oxopentanoate; 4-Fluoro-4-methyl-3-oxopentanoic acid ethyl ester; 3-Oxopentanoic acid, 4-fluoro-4-methyl-, ethyl ester; Ethyl 4-fluoro-4-methyl-3-oxovalerate; 4-Fluoro-4-methyl-3-oxovaleric acid ethyl ester; Fluorinated β-keto ester; F-Methyl levulinate derivative
EINECS	Contact for details

Quality Control

Our production of Pentanoic Acid, 4-Fluoro-4-Methyl-3-Oxo-, Ethyl Ester adheres to stringent internal quality standards to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is characterized using advanced analytical techniques including GC, HPLC, NMR, and MS. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong acids, bases, and oxidizing agents. Due to its organic ester nature, it should be handled in a fume hood and stored away from heat and ignition sources.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.