Description

n-Methoxy-n-Methyl-1-Naphthamide is a specialized chemical building block, specifically a Weinreb amide derivative of 1-naphthoic acid. This compound is of significant value in organic synthesis, primarily serving as a versatile acylating agent that provides controlled access to ketones and aldehydes. It is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors who require high-purity intermediates for complex molecule construction.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing naphthalene-based scaffolds.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides where the naphthamide moiety is a critical structural component.
• Organic Synthesis Reagent: Functions as a protected carbonyl equivalent (Weinreb amide) for the controlled introduction of 1-naphthoyl groups into target molecules via Grignard or organolithium reactions.
• Material Science Research: Employed in the creation of organic semiconductors, liquid crystals, and polymers that incorporate rigid, planar naphthalene units.
• Academic & R&D Laboratories: Serves as a high-value starting material for methodological development and the exploration of new chemical reactions in academic and industrial research settings.

Basic Information

Product Name	n-Methoxy-n-Methyl-1-Naphthamide
CAS No.	226931-26-6
Molecular Formula	C₁₄H₁₅NO₂
Molecular Weight	229.27 g/mol
Synonyms	1-Naphthalenecarboxamide, N-methoxy-N-methyl-; N-Methoxy-N-methyl-1-naphthamide; N-Methoxy-N-methylnaphthalene-1-carboxamide; N,1-Dimethoxy-N-methyl-1-naphthamide; Weinreb Amide of 1-Naphthoic Acid; 1-(N-Methoxy-N-methylcarbamoyl)naphthalene; N-Methyl-N-methoxy-1-naphthamide
EINECS	Contact for details

Quality Control

Our n-Methoxy-n-Methyl-1-Naphthamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.