Description

Benzenemethanamine, α-Ethynyl-4-Fluoro-, (Alphas)- (9Ci) is a specialized fluorinated and alkynylated benzylamine derivative, serving as a high-value synthetic building block in advanced organic chemistry. Its unique molecular architecture, featuring both a fluoro substituent and an ethynyl group, makes it a critical intermediate for constructing complex pharmacologically active molecules. This compound is primarily sought after by research institutions and pharmaceutical development teams working on novel drug candidates, particularly in areas requiring precise structural modification and fluorination strategies.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for candidates targeting central nervous system (CNS) disorders, oncology, and metabolic diseases.
• Agrochemical Research: Used in the development of new-generation herbicides and pesticides, where the fluorine atom and alkynyl group can enhance biological activity and environmental stability.
• Material Science: Serves as a monomer or functionalization agent in the creation of specialty polymers, liquid crystals, and advanced organic electronic materials.
• Chemical Biology & Proteomics: Employed as a tagging or cross-linking reagent in probe development for studying protein interactions and enzyme mechanisms.
• Academic & Contract Research: Utilized in methodological development and exploratory synthesis within university laboratories and contract research organizations (CROs).

Basic Information

Product Name	Benzenemethanamine, α-Ethynyl-4-Fluoro-, (Alphas)- (9Ci)
CAS No.	226699-03-2
Molecular Formula	C9H8FN
Molecular Weight	149.17 g/mol
Synonyms	(αS)-α-Ethynyl-4-fluorobenzenemethanamine; (S)-1-(4-Fluorophenyl)-2-propyn-1-amine; 4-Fluoro-α-ethynylbenzylamine (S)-enantiomer; (S)-(-)-α-Ethynyl-4-fluorobenzylamine; (S)-4-Fluoro-α-ethynylbenzylamine; (S)-1-(4-Fluorophenyl)prop-2-yn-1-amine; α-Ethynyl-4-fluorobenzylamine (S)-form; Benzenemethanamine, α-ethynyl-4-fluoro-, (αS)-
EINECS	Contact for details

Quality Control

Every batch of Benzenemethanamine, α-Ethynyl-4-Fluoro-, (Alphas)- (9Ci) is produced and analyzed under strict quality management protocols. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request, detailing purity, enantiomeric excess, and impurity profiles as determined by advanced analytical techniques.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.