Description

Carbamic Acid, [(1R)-3-Oxocyclopentyl]-, 1,1-Dimethylethyl Ester (9Ci) is a high-purity, chiral organic building block of significant interest in advanced synthetic chemistry. Its core value lies in its role as a key protected intermediate for the synthesis of complex, biologically active molecules, particularly in pharmaceutical research and development. This compound is essential for chemists and organizations engaged in the development of novel therapeutics, agrochemicals, and fine chemicals, where precise stereochemistry and functional group manipulation are critical.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon in the multi-step synthesis of active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and metabolic disorder targets.
• Agrochemical Research: Serves as a building block for developing novel, stereospecific pesticides and herbicides with enhanced efficacy and environmental profiles.
• Asymmetric Synthesis: Used in catalytic and stoichiometric asymmetric transformations to construct complex molecular architectures with high enantiomeric purity.
• Peptidomimetics & Prodrug Development: The carbamate and ketone functionalities make it valuable for designing peptide analogs and prodrug candidates with improved stability and bioavailability.
• Chemical Biology Probes: Employed in the synthesis of labeled compounds and molecular probes for studying enzyme mechanisms and biological pathways.
• Fine Chemical Synthesis: A versatile intermediate for creating specialty chemicals used in flavors, fragrances, and advanced materials science.

Basic Information

Product Name	Carbamic Acid, [(1R)-3-Oxocyclopentyl]-, 1,1-Dimethylethyl Ester (9Ci)
CAS No.	225641-86-1
Molecular Formula	C11H19NO3
Molecular Weight	213.27 g/mol
Synonyms	(1R)-3-Oxocyclopentylcarbamic acid tert-butyl ester; tert-Butyl N-[(1R)-3-oxocyclopentyl]carbamate; (R)-3-Oxocyclopentylcarbamic Acid tert-Butyl Ester; (R)-tert-Butyl (3-oxocyclopentyl)carbamate; (R)-N-Boc-3-aminocyclopentanone; (R)-3-((tert-Butoxycarbonyl)amino)cyclopentanone; BOC-(R)-3-Aminocyclopentanone; (R)-BOC-3-Aminocyclopentanone
EINECS	Contact for details

Quality Control

Our production of Carbamic Acid, [(1R)-3-Oxocyclopentyl]-, 1,1-Dimethylethyl Ester (9Ci) adheres to stringent quality protocols to ensure batch-to-batch consistency and high chiral purity, critical for research and development applications. All material is supported by a comprehensive Certificate of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles. We operate under a cGMP-compliant quality management system, and specifications can be tailored to meet the rigorous standards of pharmaceutical development (e.g., ICH guidelines).

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This material is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere when appropriate to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.