Description

tert-Butyl 4-Aminobenzyl(Methyl)Carbamate is a protected amine derivative, specifically a carbamate, that serves as a versatile and critical building block in advanced organic synthesis. Its primary value lies in providing a stable, orthogonal protecting group for the amine functionality, enabling complex multi-step reactions in the development of active pharmaceutical ingredients (APIs) and fine chemicals. This high-purity intermediate is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries who require reliable, high-quality raw materials for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly those containing benzylamine or aniline pharmacophores.
• Peptide Mimetics & PROTACs: Used in the construction of peptide-like molecules and Proteolysis Targeting Chimeras (PROTACs) where a protected amine is required for selective coupling.
• Agrochemical Synthesis: Intermediate in the development of advanced herbicides, fungicides, and insecticides that utilize aromatic amine chemistry.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Polymer & Material Science: Monomer or modifier for synthesizing functional polymers, such as polyurethanes or polyamides, with specific amine-related properties.
• Chemical Biology Probes: Used to create labeled or tagged molecules for studying biological pathways and protein interactions.

Basic Information

Product Name	tert-Butyl 4-Aminobenzyl(Methyl)Carbamate
CAS No.	225240-83-5
Molecular Formula	C13H20N2O2
Molecular Weight	236.31 g/mol
Synonyms	1,1-Dimethylethyl N-[(4-aminophenyl)methyl]-N-methylcarbamate; tert-Butyl N-[(4-aminophenyl)methyl]-N-methylcarbamate; 4-[[(tert-Butoxycarbonyl)(methyl)amino]methyl]aniline; BOC-4-Aminobenzyl(methyl)amine; N-Boc-N-methyl-4-aminobenzylamine; N-(tert-Butoxycarbonyl)-N-methyl-1,4-benzenedimethanamine; tert-Butyl (4-aminobenzyl)(methyl)carbamate
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-Aminobenzyl(Methyl)Carbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maximize stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.