Description

Phenoxy, 4-(Acetylamino)-3,5-Difluoro- is a high-purity fluorinated aromatic intermediate of significant importance in advanced organic synthesis. This compound matters for its role as a key building block in the development of complex molecules, particularly in the pharmaceutical and agrochemical sectors. Industries requiring precise and reliable fluorinated intermediates for research, development, and production will find this product essential for creating active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel active pharmaceutical ingredients (APIs), especially those requiring a difluorophenoxy motif for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorine atoms contribute to improved efficacy and environmental profile.
• Liquid Crystal & OLED Materials: Serves as a building block for fluorinated components in electronic display materials, contributing to desired dielectric and optical properties.
• Polymer Modification: Employed to introduce fluorinated aromatic groups into polymer chains, enhancing material properties such as chemical resistance, thermal stability, and surface characteristics.
• Organic Synthesis & Research: A versatile reagent for academic and industrial R&D labs exploring new reactions, catalysis, and the creation of complex fluorinated organic structures.
• Dye & Pigment Intermediate: Used in the synthesis of specialized fluorinated dyes and pigments that offer superior lightfastness and color properties.

Basic Information

Product Name	Phenoxy, 4-(Acetylamino)-3,5-Difluoro-
CAS No.	225107-95-9
Molecular Formula	C8H7F2NO2
Molecular Weight	187.15 g/mol
Synonyms	4'-Acetamido-3',5'-difluorodiphenyl ether; N-[3,5-Difluoro-4-phenoxyphenyl]acetamide; 3',5'-Difluoro-4'-acetamidodiphenyl ether; 4-Acetylamino-3,5-difluorophenyl phenyl ether; 4-(Acetylamino)-3,5-difluorodiphenyl ether; Acetamide, N-[3,5-difluoro-4-phenoxyphenyl]-
EINECS	Contact for details

Quality Control

Our Phenoxy, 4-(Acetylamino)-3,5-Difluoro- is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent composition suitable for sensitive synthetic applications. Certificates of Analysis (COA) detailing all specifications are available upon request, providing full traceability and compliance documentation for your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.