Description

2-Pyrrolidinecarboxamide,n-Methoxy-,(2S)-(9Ci) CAS NO 224636-66-2 is a chiral, non-natural amino acid derivative belonging to the pyrrolidine class, characterized by its specific stereochemistry at the 2-position and a methoxy-substituted carboxamide group. This compound matters as a high-value pharmaceutical intermediate and chiral building block essential for the synthesis of complex bioactive molecules. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing new active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and production of novel drug candidates, particularly for central nervous system (CNS) and metabolic disorder targets.
• Asymmetric Synthesis: Serves as a versatile building block for constructing complex molecules with defined stereochemistry in medicinal chemistry.
• Agrochemical Research: Used in the development of new, more effective pesticides and herbicides that require specific chiral configurations for activity.
• Peptidomimetics: Incorporated into the design of peptide analogs to enhance stability, bioavailability, and biological activity.
• Ligand and Catalyst Development: Acts as a precursor for creating chiral ligands and organocatalysts used in enantioselective transformations.
• Academic & Industrial R&D: A valuable reagent for chemical biology studies and process development in fine chemical synthesis.

Basic Information

Product Name	2-Pyrrolidinecarboxamide,n-Methoxy-,(2S)-(9Ci)
CAS No.	224636-66-2
Molecular Formula	C6H12N2O2
Molecular Weight	144.17 g/mol
Synonyms	(2S)-N-Methoxy-2-pyrrolidinecarboxamide; L-Proline, 1-(methoxyamino)-1-oxo- (9CI); (S)-N-Methoxypyrrolidine-2-carboxamide; 1-(Methoxyamino)-1-oxo-L-proline; (S)-N-Methoxy-2-pyrrolidinecarboxamide; (S)-N-Methoxypyrrolidine-2-carboxylic acid amide; (2S)-1-(Methoxyamino)-1-oxo-2-pyrrolidinecarboxylic acid; 224636-66-2
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. We employ advanced analytical techniques including HPLC, GC, and NMR to verify identity, purity, and chiral integrity. Certificates of Analysis (COA) with detailed batch-specific results are available upon request. Our commitment to cGMP principles and stringent quality assurance protocols guarantees reliable and consistent material for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.