Description

Cyclopropanecarboxamide, 1-Hydroxy-N,2,2-Trimethyl-, (1S)- (9Ci) is a high-purity chiral cyclopropane derivative, a key structural motif valued in advanced pharmaceutical synthesis. This compound matters as a sophisticated building block for medicinal chemistry, enabling the development of novel therapeutics with enhanced efficacy and specificity. It is primarily needed by research institutions and pharmaceutical companies engaged in the discovery and process development of new active pharmaceutical ingredients (APIs), particularly those targeting central nervous system and metabolic disorders.

Application

• Pharmaceutical Intermediate: A critical chiral synthon in the multi-step synthesis of complex drug candidates.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new therapeutic agents.
• Asymmetric Synthesis: Serves as a precursor or auxiliary in catalytic asymmetric reactions to introduce the cyclopropane moiety.
• Process Chemistry Development: Employed in scaling up synthetic routes from laboratory to pilot plant scale for clinical trial material production.
• Reference Standard: Used as an analytical standard for quality control and method validation in API manufacturing.

Basic Information

Product Name	Cyclopropanecarboxamide, 1-Hydroxy-N,2,2-Trimethyl-, (1S)- (9Ci)
CAS No.	224325-55-7
Molecular Formula	C7H13NO2
Molecular Weight	143.18 g/mol
Synonyms	(1S)-1-Hydroxy-N,2,2-trimethylcyclopropanecarboxamide; (S)-1-Hydroxy-N,2,2-trimethylcyclopropanecarboxamide; 1-Hydroxy-N,2,2-trimethylcyclopropanecarboxamide, (S)-; UNII-2V4Q8Q2Q3G; 2V4Q8Q2Q3G; Cyclopropanecarboxamide, 1-hydroxy-N,2,2-trimethyl-, (1S)-; (1S)-1-Hydroxy-2,2-dimethyl-N-methylcyclopropanecarboxamide
EINECS	Contact for details

Quality Control

Our Cyclopropanecarboxamide, 1-Hydroxy-N,2,2-Trimethyl-, (1S)- (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity. Ensure the storage area is well-ventilated.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.