Description

2-Di-T-Butylphosphino-2'-(N,n-Dimethylamino)Biphenyl is a highly specialized, air-sensitive organophosphorus ligand crucial for modern catalytic transformations. Its primary value lies in enabling highly efficient and selective cross-coupling reactions, which are fundamental to constructing complex molecules in advanced chemical synthesis. This compound is essential for R&D chemists and process engineers in the pharmaceutical, agrochemical, and advanced materials sectors who require robust and reliable catalysts for scaling up novel chemical entities.

Application

• Pharmaceutical Intermediate Synthesis: As a key ligand in Buchwald-Hartwig amination and Suzuki-Miyaura cross-coupling reactions for constructing carbon-nitrogen and carbon-carbon bonds in active pharmaceutical ingredients (APIs).
• Agrochemical Manufacturing: Used in catalytic processes to create novel herbicides, fungicides, and insecticides with improved efficacy and selectivity.
• Advanced Material Development: Facilitates the synthesis of conjugated polymers, organic light-emitting diodes (OLEDs), and other functional materials through efficient cross-coupling.
• Catalyst Precursor Preparation: Serves as a precursor for generating active palladium and other transition metal catalyst complexes in situ.
• Process Chemistry & Scale-Up: Enables more efficient, high-yielding routes for the commercial production of fine chemicals and complex organic molecules.
• Academic & Industrial R&D: A vital tool for methodological development in synthetic organic chemistry laboratories exploring new catalytic cycles.

Basic Information

Product Name	2-Di-T-Butylphosphino-2'-(N,n-Dimethylamino)Biphenyl
CAS No.	224311-49-3
Molecular Formula	C22H32N1P1
Molecular Weight	341.47 g/mol
Synonyms	DTBP-DMABP; 2-(Di-tert-butylphosphino)-2'-(N,N-dimethylamino)biphenyl; DavePhos; 2'-(Dimethylamino)-2-(di-tert-butylphosphino)biphenyl; 2-(Di-tert-butylphosphino)-2'-(dimethylamino)-1,1'-biphenyl; 2-(Di-tert-butylphosphino)-2'-(dimethylamino)biphenyl; 2-(Di-tert-butylphosphino)-2'-(N,N-dimethylamino)-1,1'-biphenyl
EINECS	Contact for details

Quality Control

Every batch of 2-Di-T-Butylphosphino-2'-(N,n-Dimethylamino)Biphenyl is manufactured and handled under strict inert atmosphere conditions to prevent oxidation. Our products undergo rigorous quality testing to ensure compliance with industry standards for high-purity organometallic reagents. Certificates of Analysis (COA) detailing purity, identity, and moisture content are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at 2-8°C in a cool, dry place. This material is light-sensitive (store away from light) and easily oxidized (store under inert atmosphere). Allow the sealed container to reach ambient temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.