Description

(2-Dichlorophosphinophenyl)Diphenylphosphine is a specialized organophosphorus compound that serves as a versatile and highly reactive ligand precursor in advanced chemical synthesis. Its molecular architecture, featuring both dichlorophosphino and diphenylphosphino groups, makes it a critical building block for constructing complex, chelating phosphine ligands used in homogeneous catalysis. This compound is essential for researchers and manufacturers in the fine chemical and pharmaceutical sectors who require precise control over catalytic processes. Its utility is particularly valued in the development of new catalytic systems for cross-coupling and hydrogenation reactions.

Application

• Ligand Synthesis: Primary precursor for synthesizing sophisticated bidentate and polydentate phosphine ligands with tailored steric and electronic properties.
• Homogeneous Catalysis: Used to create catalysts for critical organic transformations, including C-C and C-X (X = N, O) cross-coupling reactions (e.g., Suzuki, Heck, Buchwald-Hartwig).
• Hydrogenation & Asymmetric Synthesis: Foundation for developing chiral phosphine ligands used in asymmetric hydrogenation and other enantioselective catalytic processes.
• Material Science Research: Employed in the preparation of metal-organic frameworks (MOFs) and coordination polymers where specific phosphine-based linkers are required.
• Organic Electronics: Potential use in synthesizing phosphine-containing monomers or complexes for optoelectronic materials.
• Academic & Industrial R&D: A key reagent for exploring new catalytic methodologies and reaction mechanisms in both university and corporate research laboratories.

Basic Information

Product Name	(2-Dichlorophosphinophenyl)Diphenylphosphine
CAS No.	223742-01-6
Molecular Formula	C24H18Cl2P2
Molecular Weight	439.25 g/mol
Synonyms	2-(Diphenylphosphino)phenyldichlorophosphine; [2-(Diphenylphosphino)phenyl]phosphonous Dichloride; (2-Diphenylphosphinophenyl)dichlorophosphine; Dichloro[2-(diphenylphosphino)phenyl]phosphine; P,P'-(1,2-Phenylene)bis(P,P-diphenylphosphinous Chloride) (related); Bidentate Phosphine Precursor; Ligand 223742-01-6
EINECS	Contact for details

Quality Control

Every batch of (2-Dichlorophosphinophenyl)Diphenylphosphine is produced and analyzed under strict quality protocols to ensure consistency and high purity for research and process development. Our quality assurance includes rigorous analytical testing, such as NMR (1H, 31P) and HPLC analysis, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment. We adhere to cGMP principles where applicable to support our customers in regulated development environments.

Storage

Preserve in a tightly closed container, protected from light. Due to its moisture-sensitive (hygroscopic) and air-sensitive (easily oxidized) nature, this material must be stored under an inert atmosphere (argon or nitrogen) in a cool, dry place. Recommended storage temperature is 2-8°C for long-term stability. The container should be kept in a well-ventilated area and allowed to reach room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (NMR)	Conforms to structure (1H, 31P NMR)
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.