Description

3-Cyclopropoxy-Benzonitrile is a versatile aromatic nitrile derivative featuring a cyclopropoxy substituent, serving as a critical advanced intermediate in modern organic synthesis. Its unique structure makes it a valuable building block for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and agrochemicals. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific steric and electronic properties into their target compounds.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and fungicides, where the cyclopropoxy group can enhance biological activity and environmental profile.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and transition metal complexes.
• Material Science Research: Employed in the development of organic electronic materials and liquid crystals due to its rigid molecular framework.
• Chemical Biology Probes: Utilized as a scaffold for creating molecular probes to study enzyme function and biological pathways.
• Custom Synthesis and Contract Manufacturing: A high-value intermediate for custom synthesis houses serving the life sciences sector.

Basic Information

Product Name	3-Cyclopropoxy-Benzonitrile
CAS No.	223690-04-8
Molecular Formula	C10H9NO
Molecular Weight	159.19 g/mol
Synonyms	3-Cyclopropoxybenzonitrile; Benzonitrile, 3-cyclopropoxy-; m-Cyclopropoxybenzonitrile; 3-(Cyclopropoxy)benzonitrile; 3-Cyclopropoxy-phenyl cyanide; (3-Cyanophenyl) cyclopropyl ether; CAS 223690-04-8
EINECS	Contact for details

Quality Control

Our 3-Cyclopropoxy-Benzonitrile is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Production adheres to cGMP guidelines where applicable, and each lot is supported by a comprehensive Certificate of Analysis (COA). Our rigorous quality testing includes identity confirmation, purity assay, and detailed impurity profiling to meet the exacting standards of pharmaceutical and agrochemical applications. Certificates of Analysis are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.