Description

2,4-Difluorophenyl Trifluoromethyl Sulphoxide is a high-value organosulfur and organofluorine building block characterized by its unique sulfoxide and difluorophenyl motifs. This compound matters for its role in facilitating the synthesis of complex molecules, particularly in the development of advanced pharmaceuticals and agrochemicals. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the fluorine atoms and sulfoxide group enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for chiral sulfoxide ligands, which are crucial in asymmetric catalysis for enantioselective synthesis.
• Material Science Research: Employed in the synthesis of fluorinated polymers and advanced organic electronic materials due to its ability to modify electronic properties and solubility.
• Custom Synthesis and Contract Manufacturing: A critical building block for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	2,4-Difluorophenyl Trifluoromethyl Sulphoxide
CAS No.	223683-75-8
Molecular Formula	C7H3F5OS
Molecular Weight	230.16 g/mol
Synonyms	(2,4-Difluorophenyl)(trifluoromethyl)sulfoxide; Trifluoromethyl 2,4-difluorophenyl sulfoxide; 1-(Trifluoromethylsulfinyl)-2,4-difluorobenzene; α,α,α-Trifluoro-2,4-difluorophenyl methyl sulfoxide; 2,4-Difluorophenyl trifluoromethyl sulfoxide; (2,4-Difluorophenyl)(trifluoromethyl)sulphoxide
EINECS	Contact for details

Quality Control

Our 2,4-Difluorophenyl Trifluoromethyl Sulphoxide is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP standards for pharmaceutical intermediates, ensuring traceability, consistency, and reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be opaque or stored in dark conditions. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.