Description

Cathepsin V is a lysosomal cysteine protease belonging to the papain family, playing a significant role in intracellular protein degradation and antigen presentation. This enzyme is of critical importance in biochemical research for studying its specific functions in immune regulation and its potential links to various pathological conditions. It is primarily needed by researchers and developers in the fields of immunology, oncology, and drug discovery for target validation and inhibitor screening.

Application

• Biochemical Research: Used as a key reagent for studying the enzymatic activity, substrate specificity, and physiological role of Cathepsin V in cellular processes.
• Drug Discovery & Development: Serves as a target protein for high-throughput screening (HTS) to identify and characterize novel protease inhibitors for therapeutic applications.
• Immunology Studies: Employed in research focused on antigen processing and presentation pathways within the immune system.
• Oncology Research: Investigated for its role in tumor progression, invasion, and metastasis, providing insights for potential cancer biomarkers or therapeutic targets.
• Enzyme Kinetics & Mechanism Studies: Utilized to determine kinetic parameters (Km, Vmax, kcat) and elucidate the catalytic mechanism of cysteine proteases.
• Diagnostic Assay Development: Acts as a component in the development of enzymatic assays for research and potential diagnostic purposes.

Basic Information

Product Name	Cathepsin V
CAS No.	223670-00-6
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Cathepsin L2; CTSV; Cathepsin V (Human); Cathepsin L2 (Human); EC 3.4.22.43; Cysteine protease Cathepsin V; Lysosomal cysteine protease V
EINECS	Contact for details

Quality Control

Our Cathepsin V is produced and tested under stringent quality management protocols to ensure batch-to-batch consistency and high biological activity. Each lot undergoes comprehensive analysis, including assessment of purity and specific activity. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to support your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to minimize exposure to atmospheric moisture. For short-term use, aliquoting is recommended to avoid repeated freeze-thaw cycles.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (Activity)	Conforms
Specific Activity	≥ [Value] units/mg protein
Purity (SDS-PAGE)	≥ 90%
Protein Content (Bradford)	≥ [Value] mg/vial
Endotoxin Level (LAL)	< 1.0 EU/μg
Solubility	Soluble in appropriate aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.