Description

Alanine, n-(2,4-Difluorobenzoyl)-2-Methyl- is a specialized, high-purity fluorinated amino acid derivative. This compound is a critical pharmaceutical intermediate, valued for its role in the synthesis of complex active pharmaceutical ingredients (APIs). It is primarily required by research institutions and pharmaceutical manufacturers engaged in the development of new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in medicinal chemistry research.
• API Synthesis: Used in the production route for Active Pharmaceutical Ingredients (APIs) that incorporate fluorinated motifs for enhanced metabolic stability and bioavailability.
• Peptidomimetics Research: Serves as a modified amino acid in the design and study of peptide analogs and peptidomimetics.
• Chemical Biology Probes: Utilized in the development of labeled compounds and probes for studying biological mechanisms and target engagement.
• Process Development: Employed in process chemistry for scaling up synthetic routes from laboratory to pilot and commercial production.
• Custom Synthesis: A starting material for custom chemical synthesis services catering to the pharmaceutical and biotechnology sectors.

Basic Information

Product Name	Alanine, n-(2,4-Difluorobenzoyl)-2-Methyl-
CAS No.	223444-77-7
Molecular Formula	C11H11F2NO3
Molecular Weight	243.21 g/mol
Synonyms	2-Methyl-N-(2,4-difluorobenzoyl)alanine; N-(2,4-Difluorobenzoyl)-2-methylalanine; 2-Methylalanine, N-(2,4-difluorobenzoyl)-; (2-Methylalanyl)(2,4-difluorophenyl)methanone; Alanine derivative, N-(2,4-difluorobenzoyl)-2-methyl-; 2,4-Difluoro-N-(1-carboxy-1-methylethyl)benzamide; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our Alanine, n-(2,4-Difluorobenzoyl)-2-Methyl- is produced under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with full traceability are provided and available upon request to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.