Description

(R)-Benzyl 2-Oxopyrrolidin-3-Ylcarbamate is a high-purity chiral building block and pharmaceutical intermediate. This compound is critical for the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs) and other fine chemicals. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing novel therapeutic agents and advanced materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and production of enantiomerically pure drugs, particularly those targeting the central nervous system.
• API Synthesis: Used in the synthetic pathways for developing novel γ-aminobutyric acid (GABA) analogues and other bioactive molecules.
• Asymmetric Catalysis Research: Serves as a precursor or ligand in the development of new asymmetric catalytic processes.
• Agrochemical Development: Employed in the synthesis of chiral active ingredients for advanced crop protection products.
• Academic & Industrial R&D: A valuable reagent for medicinal chemistry and process chemistry research in both academic and corporate laboratories.
• Custom Synthesis: Used as a starting material for the contract manufacturing of complex, high-value specialty chemicals.

Basic Information

Product Name	(R)-Benzyl 2-Oxopyrrolidin-3-Ylcarbamate
CAS No.	223407-18-9
Molecular Formula	C13H16N2O3
Molecular Weight	248.28 g/mol
Synonyms	(R)-Benzyl 3-((benzyloxy)carbonylamino)-2-oxopyrrolidine-1-carboxylate; (3R)-1,3-Pyrrolidinedicarboxylic acid, 3-[[(phenylmethoxy)carbonyl]amino]-, 1-(phenylmethyl) ester; (R)-1-Benzyl 3-benzyloxycarbonylamino-2-oxopyrrolidine-3-carboxylate; (R)-N-Cbz-3-Aminopyrrolidin-2-one; (R)-3-[(Benzyloxycarbonyl)amino]-2-oxo-1-pyrrolidinecarboxylic Acid Benzyl Ester; (R)-CBZ-3-Amino-2-pyrrolidinone; (R)-1-Benzyl 3-[(benzyloxy)carbonyl]-2-oxo-3-pyrrolidinecarboxylate
EINECS	Contact for details

Quality Control

Our (R)-Benzyl 2-Oxopyrrolidin-3-Ylcarbamate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D and cGMP intermediate applications. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The product is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if specified.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.