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4-Hydroxy-1-Methylpyrrolidin-2-One CAS NO 222856-39-5


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CAS No.:222856-39-5

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

4-Hydroxy-1-Methylpyrrolidin-2-One is a versatile pyrrolidone derivative, a high-purity building block of significant interest in advanced organic synthesis. Its unique structure, featuring both a hydroxyl group and a lactam ring, makes it a valuable precursor for creating complex molecules with tailored properties. This compound is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries, particularly for developing novel active pharmaceutical ingredients (APIs) and specialty intermediates.

Application

  • Pharmaceutical Intermediate: A key chiral building block in the synthesis of complex drug molecules, particularly those targeting the central nervous system.
  • Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, where its heterocyclic structure contributes to biological activity.
  • Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
  • Polymer Modification: Acts as a functional monomer or additive to introduce polar, hydrophilic characteristics into specialty polymers and coatings.
  • Chemical Research & Development: A valuable reagent in academic and industrial R&D for exploring new synthetic pathways and novel heterocyclic compounds.
  • Electrolyte Additive: Investigated for use in advanced battery formulations to improve stability and performance of electrolytes.

Basic Information

Product Name 4-Hydroxy-1-Methylpyrrolidin-2-One
CAS No. 222856-39-5
Molecular Formula C5H9NO2
Molecular Weight 115.13 g/mol
Synonyms 1-Methyl-4-hydroxypyrrolidin-2-one; 4-Hydroxy-1-methyl-2-pyrrolidinone; (4-Hydroxy-1-methylpyrrolidin-2-one); 1-Methyl-4-hydroxy-2-pyrrolidone; 4-Hydroxy-N-methyl-2-pyrrolidone; 2-Pyrrolidinone, 4-hydroxy-1-methyl-; Contact for details on additional trade names.
EINECS Contact for details

Quality Control

Our 4-Hydroxy-1-Methylpyrrolidin-2-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed to prevent absorption of atmospheric moisture.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Assay (HPLC) ≥ 98.0%
Water Content (KF) ≤ 1.0%
Residue on Ignition ≤ 0.1%
Heavy Metals (as Pb) ≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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