Description

2-Bromo-6-Chloro-4-Fluoroanisole is a high-purity, multi-halogenated anisole derivative serving as a critical advanced intermediate in organic synthesis. Its value lies in providing a versatile, functionalized aromatic scaffold for constructing complex molecules, particularly in pharmaceutical research and development. This compound is essential for chemists and manufacturers in the agrochemical, pharmaceutical, and specialty chemical industries who require precise building blocks for active ingredient synthesis.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly for candidates containing complex halogenated aromatic systems.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides where the bromo, chloro, and fluoro substituents impart specific biological activity and stability.
• Liquid Crystal & OLED Material Precursor: Serves as a building block for synthesizing fluorinated and halogenated organic compounds used in electronic display technologies.
• Organic Synthesis Reagent: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic aromatic substitution due to its reactive halogen sites.
• Dye & Pigment Intermediate: Utilized in the synthesis of specialized halogenated dyes and pigments for high-performance applications.
• Research & Development: A valuable compound for academic and industrial R&D labs exploring new synthetic methodologies and material properties.

Basic Information

Item	Detail
Product Name	2-Bromo-6-Chloro-4-Fluoroanisole
CAS No.	222712-93-8
Molecular Formula	C7H5BrClFO
Molecular Weight	239.47 g/mol
Synonyms	1-Bromo-3-chloro-5-fluoro-2-methoxybenzene; 2-Methoxy-3-chloro-5-fluorobromobenzene; 3-Chloro-5-fluoro-2-methoxybromobenzene; 2-Bromo-6-chloro-4-fluoro-1-methoxybenzene; Anisole, 2-bromo-6-chloro-4-fluoro-; Benzene, 1-bromo-3-chloro-5-fluoro-2-methoxy-
EINECS	Contact for details

Quality Control

Every batch of 2-Bromo-6-Chloro-4-Fluoroanisole is manufactured under strict quality management systems and undergoes rigorous analytical testing to ensure consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our commitment to quality assurance supports your compliance needs in regulated synthesis pathways.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging during storage and handling.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.