Description

(4-Fluorophenylmethanesulfonyl)-Acetic Acid is a specialized organic sulfonyl compound featuring a fluorinated aromatic ring, making it a valuable building block in advanced chemical synthesis. This compound matters for its role as a key intermediate in the development of active pharmaceutical ingredients (APIs) and other high-value fine chemicals. It is primarily needed by research and development teams, process chemists, and manufacturers in the pharmaceutical, agrochemical, and material science industries seeking to incorporate fluorinated sulfonyl motifs into novel molecules.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammatory diseases, and metabolic conditions.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and pesticides, where the fluorine atom and sulfonyl group can enhance biological activity and environmental stability.
• Material Science: Serves as a monomer or functionalization agent in the creation of specialty polymers, coatings, and advanced materials with specific surface properties.
• Chemical Synthesis Building Block: Employed in organic synthesis for constructing complex molecules via reactions at the sulfonyl or carboxylic acid functional groups.
• Bioconjugation & Probe Development: Utilized in biochemical research for modifying peptides, proteins, or other biomolecules to create probes or conjugates for diagnostic applications.

Basic Information

Product Name	(4-Fluorophenylmethanesulfonyl)-Acetic Acid
CAS No.	222639-41-0
Molecular Formula	C9H9FO4S
Molecular Weight	232.23 g/mol
Synonyms	2-[(4-Fluorophenyl)methylsulfonyl]acetic acid; [(4-Fluorophenyl)methanesulfonyl]acetic acid; 4-Fluorobenzylsulfonylacetic acid; (p-Fluorobenzylsulfonyl)acetic acid; 2-((4-Fluorobenzyl)sulfonyl)acetic acid; 4-Fluoro-α-(sulfomethyl)benzenemethanol γ-sultone (tautomer); FBSAA; 222639-41-0
EINECS	Contact for details

Quality Control

Our (4-Fluorophenylmethanesulfonyl)-Acetic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and production. A comprehensive Certificate of Analysis (COA) detailing purity, impurity profile, and physical characteristics is provided with each shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.