Description

4-Bromo-2-Fluoro-1,3-Dimethoxybenzene is a high-purity halogenated dimethoxybenzene derivative, serving as a critical building block in advanced organic synthesis. Its unique substitution pattern makes it an invaluable intermediate for constructing complex molecules with precise electronic and steric properties. This compound is primarily sought after by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: Key synthon for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders and oncology.
• Agrochemical Synthesis: Used in the production of advanced herbicides and fungicides, where the bromo and fluoro substituents modulate biological activity.
• Ligand and Catalyst Development: Serves as a precursor for sophisticated ligands in transition metal catalysis and materials science applications.
• Functional Material Research: Employed in the development of organic semiconductors, liquid crystals, and other specialty electronic materials.
• Custom Synthesis and Contract Manufacturing: A vital starting material for custom synthesis houses serving the fine chemical and life science sectors.

Basic Information

Product Name	4-Bromo-2-Fluoro-1,3-Dimethoxybenzene
CAS No.	222547-68-4
Molecular Formula	C8H8BrFO2
Molecular Weight	235.05 g/mol
Synonyms	1-Bromo-4-fluoro-2,5-dimethoxybenzene; 2,5-Dimethoxy-4-bromofluorobenzene; 4-Bromo-2-fluoro-1,3-dimethoxybenzene; Benzene, 4-bromo-2-fluoro-1,3-dimethoxy-; 4-Bromo-2-fluororesorcinol dimethyl ether
EINECS	Contact for details

Quality Control

We maintain stringent quality control protocols for all our fine chemical intermediates. Production of 4-Bromo-2-Fluoro-1,3-Dimethoxybenzene adheres to current Good Manufacturing Practices (cGMP) where applicable, ensuring batch-to-batch consistency and reliability. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. Our quality management system is designed to meet the exacting standards of global pharmaceutical and agrochemical supply chains.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residue on Ignition	< 0.1%
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.