Description

1-Piperidineaceticacid,4-[[(9H-Fluoren-9-Ylmethoxy)Carbonyl]Amino]-(9Ci) is a specialized, high-purity building block designed for advanced organic synthesis. This compound matters because it serves as a critical intermediate for constructing complex molecules, particularly in pharmaceutical research and development. It is primarily needed by medicinal chemists and process development scientists working on novel active pharmaceutical ingredients (APIs) and peptide-based therapeutics.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly those targeting neurological and metabolic disorders.
• Peptide Chemistry: Used as a protected amino acid derivative for solid-phase peptide synthesis (SPPS) and fragment coupling.
• Fmoc-Protection Strategy: The 9-fluorenylmethoxycarbonyl (Fmoc) group enables orthogonal protection schemes essential for complex, multi-step syntheses.
• Chemical Biology Research: Employed in the development of molecular probes, enzyme inhibitors, and labeled compounds for biological studies.
• Process Chemistry Development: Serves as a starting material for scaling up the production of key pharmacophores under Good Manufacturing Practice (GMP) conditions.
• Custom Synthesis: A foundational reagent for contract research and manufacturing organizations (CROs/CMOs) producing bespoke compounds for clients.

Basic Information

Item	Details
Product Name	1-Piperidineaceticacid,4-[[(9H-Fluoren-9-Ylmethoxy)Carbonyl]Amino]-(9Ci)
CAS No.	221352-82-5
Molecular Formula	C22H24N2O4
Molecular Weight	380.44 g/mol
Synonyms	Fmoc-4-Amino-1-piperidineacetic acid; 4-[(Fmoc-amino)]-1-piperidineacetic acid; 1-Piperidineacetic acid, 4-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]-; 4-(Fmoc-amino)piperidine-1-acetic acid; Nα-Fmoc-4-aminopiperidine-1-acetic acid; Fmoc-Ahppa-OH; (4-{[(9H-Fluoren-9-ylmethoxy)carbonyl]amino}piperidin-1-yl)acetic acid
EINECS	Contact for details

Quality Control

Our 1-Piperidineaceticacid,4-[[(9H-Fluoren-9-Ylmethoxy)Carbonyl]Amino]-(9Ci) is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity suitable for research and development. We employ advanced analytical techniques including HPLC, NMR, and mass spectrometry for comprehensive characterization. Certificates of Analysis (COA) with detailed specifications are provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled under dry, inert conditions to maintain stability and purity. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.