Description

2'-(Dicyclohexylphosphino)Acetophenone is a specialized organophosphorus ligand, a key building block in modern catalytic chemistry. This compound matters for its crucial role in facilitating highly selective cross-coupling reactions, enabling the efficient synthesis of complex organic molecules. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for catalyst design and fine chemical production.

Application

• As a precursor or ligand in the development of palladium and other transition metal catalysts for cross-coupling reactions (e.g., Suzuki, Heck, Negishi).
• Utilized in academic and industrial R&D for exploring new catalytic systems and reaction methodologies.
• Employed in the synthesis of active pharmaceutical ingredients (APIs) and complex organic intermediates requiring high selectivity.
• Used in the preparation of specialty chemicals and functional materials, including OLED materials and liquid crystals.
• Application in asymmetric catalysis research for the production of chiral molecules.
• Serves as a key intermediate for modifying and tuning the steric and electronic properties of phosphine ligands.

Basic Information

Product Name	2'-(Dicyclohexylphosphino)Acetophenone
CAS No.	221187-50-4
Molecular Formula	C₂₀H₂₉OP
Molecular Weight	316.42 g/mol
Synonyms	2-Acetylbenzyldicyclohexylphosphine; (2-Acetylphenyl)dicyclohexylphosphine; Dicyclohexyl(2-acetylphenyl)phosphine; 2-(Dicyclohexylphosphino)acetophenone; Acetophenone, 2'-(dicyclohexylphosphino)-; 221187-50-4; Phosphine, dicyclohexyl(2-acetylphenyl)-
EINECS	Contact for details

Quality Control

Our 2'-(Dicyclohexylphosphino)Acetophenone is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including NMR (¹H, ³¹P), HPLC, and GC analysis, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) in a cool, dry, and well-ventilated place. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
¹H NMR	Conforms
³¹P NMR	Conforms
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.