Description

Benzenebutanoic Acid, 2,6-Difluoro-B-Oxo-, Ethyl Ester is a high-purity fluorinated aromatic ester, serving as a critical advanced pharmaceutical intermediate for the synthesis of complex active molecules. Its value lies in providing a versatile, fluorine-containing scaffold that enables the fine-tuning of drug properties such as metabolic stability, bioavailability, and target binding affinity. This compound is primarily needed by R&D laboratories and contract manufacturing organizations (CMOs) in the pharmaceutical and agrochemical sectors for developing next-generation therapeutics and crop protection agents.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Research: Used in developing advanced herbicides and pesticides, where the fluorine atoms enhance biological activity and environmental persistence.
• Material Science: Serves as a monomer or precursor for specialty polymers and liquid crystals with unique optical and electronic properties.
• Organic Synthesis: A versatile reagent for constructing complex fluorinated aromatic structures in academic and industrial research settings.
• Fluorine Chemistry: Acts as a standard or reference compound in methodological studies involving fluorination or esterification reactions.

Basic Information

Product Name	Benzenebutanoic Acid, 2,6-Difluoro-B-Oxo-, Ethyl Ester
CAS No.	221121-46-6
Molecular Formula	C₁₂H₁₂F₂O₃
Molecular Weight	242.22 g/mol
Synonyms	Ethyl 2,6-Difluoro-β-oxobenzenebutanoate; 4-(2,6-Difluorophenyl)-4-oxobutanoic Acid Ethyl Ester; 2,6-Difluoro-β-oxobenzenebutanoic Acid Ethyl Ester; Ethyl 4-(2,6-Difluorophenyl)-4-oxobutanoate; Butanoic acid, 4-(2,6-difluorophenyl)-4-oxo-, ethyl ester; 221121-46-6; Benzenebutanoic acid, 2,6-difluoro-β-oxo-, ethyl ester
EINECS	Contact for details

Quality Control

Our production of Benzenebutanoic Acid, 2,6-Difluoro-B-Oxo-, Ethyl Ester adheres to stringent ISO 9001 quality management principles, ensuring batch-to-batch consistency and traceability. Every lot undergoes comprehensive analytical characterization, including HPLC for purity and identity confirmation via NMR and Mass Spectrometry. A detailed Certificate of Analysis (COA) documenting all critical quality attributes is provided with each shipment to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and sources of ignition. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.