Description

Tricyclo[3.2.1.02,4]Octane, 3-Ethynyl-, (1Alpha,2Beta,3Alpha,4Beta,5Alpha)- (9Ci) is a highly specialized, strained polycyclic organic compound featuring a unique tricyclic framework with an ethynyl (acetylene) substituent. This complex molecular architecture makes it a valuable and versatile advanced intermediate for sophisticated organic synthesis, particularly in the development of novel materials and active pharmaceutical ingredients (APIs). It is primarily sought by research chemists and process development scientists in pharmaceutical R&D, agrochemical discovery, and advanced material science for constructing complex molecular scaffolds.

Application

• Pharmaceutical Intermediate: Serves as a key building block for synthesizing novel drug candidates with complex polycyclic core structures, potentially for central nervous system (CNS) or anti-viral applications.
• Agrochemical Research: Used in the discovery and development of new herbicides, fungicides, or insecticides that require unique, three-dimensional molecular shapes for target specificity.
• Material Science Precursor: Acts as a monomer or cross-linking agent in the synthesis of specialty polymers, resins, or cage-like frameworks for advanced materials.
• Ligand Synthesis: The ethynyl group provides a handle for "click chemistry" (e.g., CuAAC reactions) to attach this complex scaffold to other molecules, surfaces, or biomolecules, useful in chemical biology and sensor development.
• Academic & Industrial R&D: Employed in fundamental organic chemistry research to study strain, reactivity, and novel reaction pathways of polycyclic systems.
• Fine Chemical Synthesis: Utilized in the multi-step synthesis of complex natural product analogs or other high-value specialty chemicals.

Basic Information

Product Name	Tricyclo[3.2.1.02,4]Octane, 3-Ethynyl-, (1Alpha,2Beta,3Alpha,4Beta,5Alpha)- (9Ci)
CAS No.	221100-80-7
Molecular Formula	C10H10
Molecular Weight	130.19 g/mol
Synonyms	(1α,2β,3α,4β,5α)-3-Ethynyltricyclo[3.2.1.02,4]octane; 3-Ethynyltricyclo[3.2.1.02,4]octane; Tricyclo[3.2.1.02,4]octane, 3-ethynyl-, (1α,2β,3α,4β,5α)-; 3-Ethynyltricyclo[3.2.1.0²,⁴]octane; Ethynyltricyclooctane; Advanced strained polycyclic intermediate; CAS 221100-80-7
EINECS	Contact for details

Quality Control

Every batch of this high-purity intermediate is produced and analyzed under strict quality management protocols. We provide comprehensive Certificates of Analysis (COA) that detail purity, identity, and impurity profiles, ensuring traceability and consistency for your critical research and development processes. Our quality systems are designed to support cGMP and ISO standards for advanced chemical manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). For long-term storage, consider maintaining the material under an inert atmosphere (e.g., nitrogen or argon) to preserve stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure (¹H NMR, ¹³C NMR)
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.